Elimination of Chromosome Aberrations from Human Lymphocytes

Elimination of chromosome aberrations from human lymphocytes.

Chromosome Aberrations in B Lymphocytes

Although chromosome aberrations in T lymphocytes and bone marrow cells have been reported in atomic bomb survivors, the presence of chromosome abnormalities has not been demonstrated in B lymphocytes because of the technical difficulties involved in B-lymphocyte separation. A method for detecting chromosome aberrations in B lymphocytes was established by “stimulation” of B lymphocytes with Epst...

Chromosome aberrations in human lymphocytes irradiated with heavy ions

Because of the increasing use of heavy ions in cancer therapy and for the planning of manned space travels, a realistic estimate of the health risks associated with particle exposure is indispensable. The standard method to quantify the exposed dose and to assess the health risks of radiation is the analysis of chromosome aberrations in peripheral blood lymphocytes at the first post-irradiation...

Ionizing radiation induces chromosome aberrations in G0 human peripheral lymphocytes

Blood lymphocytes from xeroderma pigmentosum (XP) and Fanconi anemia (FA) patients were assessed for their sensitivity to ionizing radiation by estimating the frequency of X-ray (1 and 2 Gy)-induced chromosome aberrations (CA). The frequencies of aberrations in the whole genome were estimated in Giemsa-stained preparations of lymphocytes irradiated at G0 or G2 stages. The frequencies of translo...

Drinking beer reduces radiation-induced chromosome aberrations in human lymphocytes.

We here investigated and reported the effects of beer drinking on radiation-induced chromosome aberrations in blood lymphocytes. Human blood that was collected either before or after drinking a 700 ml beer was in vitro irradiated with 200 kVp X rays or 50 keV/microm carbon ions. The relation between the radiation dose and the aberration frequencies (fragments and dicentrics) was significantly (...